(1R,2R,3S,5R)-3-Amino-2,6,6-trimethylbicyclo[3.1.1]heptan-2-... - Names and Identifiers
Name | (1R,2R,3S,5R)-3-Amino-2,6,6-trimethylbicyclo[3.1.1]heptan-2-ol
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Synonyms | (1R,2R,3S,5R)-3-amino-2,6,6-trimethyl-norpinan-2-ol (1R,2R,3S,5R)-3-Amino-2,6,6-trimethylbicyclo[3.1.1]heptan-2-ol (1R,2R,3S,5R)-3-Amino-2,6,6-trimethylbicyclo[3.1.1]heptan-2-... Bicyclo[3.1.1]heptan-2-ol, 3-amino-2,6,6-trimethyl-, (1R,2R,3S,5R)- bicyclo[3.1.1]heptan-2-ol, 3-amino-2,6,6-trimethyl-, (1R,2R,3S,5R)-
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CAS | 168286-10-0
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InChI | InChI=1/C10H19NO/c1-9(2)6-4-7(9)10(3,12)8(11)5-6/h6-8,12H,4-5,11H2,1-3H3/t6-,7-,8+,10-/m1/s1 |
(1R,2R,3S,5R)-3-Amino-2,6,6-trimethylbicyclo[3.1.1]heptan-2-... - Physico-chemical Properties
Molecular Formula | C10H19NO
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Molar Mass | 169.26 |
Density | 1.016g/cm3 |
Boling Point | 239.502°C at 760 mmHg |
Flash Point | 98.648°C |
Vapor Presure | 0.007mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.505 |
(1R,2R,3S,5R)-3-Amino-2,6,6-trimethylbicyclo[3.1.1]heptan-2-... - Introduction
(1R,2R,3S,5R)-3-Amino-2,6,6-trimethylbicyclo[3.1.1]heptan-2-ol, also known as mentholamine, is an organic compound. Its molecular formula is C10H19NO and its molecular weight is 169.26g/mol.
Nature:
-Appearance: colorless crystal or white crystalline powder
-Melting Point: 66-70 ℃
-Boiling point: 290-293 ℃
-Solubility: Slightly soluble in water, soluble in alcohol, ether and sulfuric acid.
Use:
-Pharmaceutical field: mentholamine can be used as painkillers, narcotics, etc.
-Cosmetics and personal care products: Due to its cooling and soothing properties, it is commonly used in the manufacture of oral care products, skin treatments, skin care products, etc.
-Food and condiments: mentholamine is used as a flavoring additive, mainly in chewing gum, mints and other products.
Method:
(1R,2R,3S,5R)-3-Amino-2,6,6-trimethylbicyclo[3.1.1]heptan-2-ol can be obtained by the reaction of menthol (menthol) with ammonia. First, under alkaline conditions, menthol and ammonia water undergo a partial vicinal amino substitution reaction from the substrate to the reaction product. Then, by acidification, mentholamine is produced.
Safety Information:
mentholamine is generally considered safe, but the following should be noted:
-Avoid contact with eyes, skin and mucous membranes.
-Use with appropriate protective equipment, such as gloves and goggles.
-Store in a dry, cool place and avoid contact with flammable substances.
Last Update:2024-04-09 21:01:54